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AnthologyRX

NAD+

Help boost energy, sharpen focus and support faster recovery with NAD+ injections at home.

Your treatment plan

From $159/month equivalent

$477 billed every 3 months3-month commitment$199 billed monthly also availableAll fees includedView plan details
  • Licensed clinicians
  • Compounded by a licensed 503A pharmacy
  • No clinic visit

Questions before you start?

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What will I pay?

Standard plan price$159 per month equivalent, billed $477 every 3 months. 3-month commitment.

Billing options and renewal

The standard NAD+ price is $199 billed monthly, or $477 paid up front every three months ($159 per month equivalent; a three-month commitment). These are recurring prices before any eligible first-order discount. A first-order offer reduces that order only; renewal uses the standard price for the chosen plan. A monthly equivalent is not a monthly charge.

View full plan details

What should I know about this treatment?

Help boost energy, sharpen focus and support faster recovery with NAD+ injections at home.

Read the evidence and its limitations

What should I review before starting?

A licensed clinician reviews your health history and medications and determines whether treatment is appropriate for you.

Read the full Important Safety Information

How do I request NAD+ online?

Complete the online assessment with your health history, current medications and treatment goals. A licensed clinician reviews the information and decides whether to prescribe. If prescribed, a licensed pharmacy prepares and ships your medication.

See how care works
What It Is

Central to cellular energy. Not a shortcut to more of it.

NAD+, nicotinamide adenine dinucleotide, is not a supplement trend your body had never heard of. It is a coenzyme already present in cells throughout the body and involved in the chemistry that converts nutrients into usable cellular energy.

That central role is why NAD+ attracts so much attention in longevity conversations.

It also participates in enzyme systems involved in DNA repair, cellular stress responses, and metabolic regulation. Those mechanisms are real enough to be interesting without turning them into a promise that a compounded injection will make you feel younger, think faster, or recover like you did ten years ago.

This prescription uses subcutaneous delivery rather than an oral supplement route. Subcutaneous administration bypasses the oral route and places the compounded prescription into tissue rather than through digestion. That is a real formulation difference, but it does not by itself establish a particular clinical outcome. Your provider decides whether the formulation has a reasonable place in your broader plan.

You receive the supplies, storage instructions, administration guidance, and clinician follow-up needed to use the prescription as directed. Outcome expectations remain tied to research and your individual response.

Read the evidence
Who It's For

For the longevity reader who wants the biology before the promise.

01

The Fundamentals Are Already Handled

Sleep, training, nutrition, and ordinary medical care are not being neglected. You are interested in cellular-energy biology as a next conversation, not as a substitute for the basics.

02

The NAD+ Reader With Better Questions

You have seen dramatic claims about energy, focus, aging, and recovery. You want a clinician who can separate what NAD+ does inside cells from what a prescription has actually been shown to do for a person.

03

The Cellular-Energy Realist

You are less interested in chasing a feeling than in understanding whether an endogenous coenzyme with real metabolic importance belongs in a clinician-guided plan. You want the biology kept specific and the expectations kept honest.

Compounded NAD+ is not an FDA-approved drug product. Candidacy and dose are determined by a licensed provider from your full intake, and results vary.

This might not be the right fit if:
  • You have an active cancer or are being treated for one. NAD+ can support the same cellular pathways that let cells multiply, so this needs oncology input first.
  • You are pregnant or breastfeeding.
  • You have significant kidney or liver disease. Talk with your provider before starting any injectable.
  • You take a medication or carry a condition that deserves a closer look before adding an injectable compound.

Your intake screens for all contraindications. Every candidate is evaluated by a licensed clinician before any prescription is issued. No prescription is issued without clearance.

Your Plan

NAD+, prescribed with care.

Compounded by a licensed 503A pharmacy. Prescribed by a licensed provider after clinical review.

One price covers your consultation, provider review, medication if prescribed, pharmacy fulfillment, shipping and follow-up. All fees included.
Format
Injection
Strength
100 mg/mL
Total plan quantity
30 mL
Billed amount
$477 every 3 months
Monthly equivalent
$159 per month
Commitment
3 months
Monthly option
$199 billed monthly · 10 mL total plan quantity
Fees
Included in the plan price

Strength describes the preparation. Total plan quantity is the amount included in that plan, not your dose or dosing schedule. Follow the directions on your prescription.

Your subscription renews at your selected billing interval. Cancel through your member dashboard before the next billing date to stop future charges. Cancellation does not refund the current billing period. See cancellation and refund terms.

Have a question about this plan?

Billing

Our support team can help with plan prices, billing and portal access.

Ask about billing

Shipping

Contact AnthologyRX support for help checking a shipment.

Get shipment help

Clinical questions

Message your provider about dosing, side effects, your response or changes in your health.

Open patient portal

New to AnthologyRX? Ask our team about getting started.

The people behind your care

Guidance from the first question onward.

Independent clinical care

Licensed clinicians affiliated with Arora Health & Aesthetics, LLC review your health history, medications and goals, then discuss whether NAD+ or another approach fits your needs.

Medical information on this page reviewed by Dr. Dylan Russell, MD, Chief Health Officer on . Your prescribing clinician provides your individual care.

Verify Dr. Russell's medical license

Pharmacy quality that matters

Prepared to your prescription by a licensed compounding pharmacy. Our partners have verified quality programs covering identity, potency, independent testing and batch documentation, with sterility and endotoxin controls for injectable preparations.

Compounded preparations are not FDA-approved. Pharmacy quality controls and your clinician's evaluation of treatment evidence each have a role in your care.

Pharmacy & fulfillment

Listed dispensing pharmacy

Availability depends on your prescription and location. For pharmacy questions, contact our team.

Explore our pharmacy quality standards

A direct line for follow-up

Message your provider through the patient portal about dosing, side effects, your response or changes in your health. Contact AnthologyRX support for billing, shipment or portal-access help.

The Evidence

What the research shows

Pilot study · eleven healthy men

Intravenous NAD+ showed no measurable plasma rise for the first two hours.

750 mg
by six-hour intravenous infusion in eight of eleven men
The detail

In a human pilot study of eleven healthy men aged 30 to 55, the eight who received 750 mg of NAD+ by six-hour intravenous infusion showed no measurable rise in plasma NAD+ or its metabolites for the first two hours, with increased urinary excretion of NAD+ and methylnicotinamide detected at six hours.1

Randomized placebo-controlled trial · 180 adults · seven days

In heart failure, intravenous NAD+ improved ejection fraction; secondary endpoints did not reach significance.

45.44 vs 42.44 percent
left ventricular ejection fraction at one month, NAD+ versus placebo
The detail

In a single-center randomized, placebo-controlled trial of 180 adults with heart failure from ischemic cardiomyopathy, intravenous NAD+ at 10 mg daily for seven days improved left ventricular ejection fraction at one month compared with placebo, 45.44 percent versus 42.44 percent, while the secondary endpoints of NT-proBNP, major adverse cardiac and cerebrovascular events, and functional class showed trends that did not reach statistical significance.2

Tissue study · 49 human donors

In human skin tissue, NAD+ levels correlated negatively with age.

49 donors
pelvic skin samples from newborn to 77 years of age
The detail

In pelvic skin tissue from 49 human donors ranging from newborn to 77 years of age, NAD+ levels correlated negatively with age in both males and females, alongside age-associated increases in DNA damage and in PARP activity.3

Randomized double-blind crossover trial · six weeks

Oral nicotinamide riboside, a precursor, raised blood NAD+ by about 60 percent.

60 percent
rise in NAD+ in peripheral blood mononuclear cells versus placebo
The detail

In a two-period, six-week randomized, double-blind, placebo-controlled crossover trial in healthy middle-aged and older adults, 1000 mg per day of oral nicotinamide riboside, a precursor rather than NAD+ itself, was well tolerated and raised NAD+ in peripheral blood mononuclear cells by approximately 60 percent compared with placebo.4

Randomized double-blind trial · ten weeks

Oral nicotinamide mononucleotide increased insulin-stimulated glucose disposal in women with prediabetes.

The detail

In a ten-week randomized, double-blind, placebo-controlled trial in postmenopausal women with prediabetes who were overweight or obese, oral nicotinamide mononucleotide, also a precursor rather than NAD+ itself, increased insulin-stimulated glucose disposal measured by hyperinsulinemic-euglycemic clamp and increased skeletal muscle insulin signaling, while placebo did not.5

Systematic review · 113 intervention studies

Oral nicotinamide riboside and mononucleotide raised NAD metabolites; functional outcomes were often null.

113 studies · 33 in humans
intervention studies in the review, including human intervention studies
The detail

In a PRISMA-guided systematic review of 113 intervention studies, including 33 human intervention studies, oral nicotinamide riboside and nicotinamide mononucleotide consistently raised NAD-related metabolites in humans and were generally well tolerated, while effects on functional, metabolic, and vascular outcomes were heterogeneous and often null.6

What it does not show

Evidence gap · systematic review

No randomized trial has tested injected NAD+ for energy, cognition, healthy aging or recovery.

The detail

No randomized controlled trial has evaluated injected or infused NAD+ for energy, cognition, healthy aging, or recovery, which is the reason most people consider this prescription. A systematic review of the literature through October 2025 identified no outcomes trial of intravenous or intramuscular NAD+ for anti-aging or wellness indications.

Applicability · route and dose

No published human study reports what subcutaneous NAD+ does to tissue levels or outcomes.

The detail

The human data on NAD+ itself come from routes and doses that are not what is offered here: a 750 mg six-hour intravenous infusion in a pilot study, and a seven-day course of intravenous NAD+ in patients hospitalized with heart failure from ischemic cardiomyopathy. No published human study reports what subcutaneous NAD+ does to tissue NAD+ levels or to any clinical outcome.

Applicability · molecule and route

The most rigorous trials tested oral precursors, not NAD+ itself.

The detail

The most rigorous human trials in this category tested oral precursors, nicotinamide riboside and nicotinamide mononucleotide, rather than NAD+ itself. Those are different molecules given by a different route, and their results do not establish what an NAD+ injection does.

Applicability · correlation

Correlation in skin samples does not establish that raising NAD+ by injection reverses anything.

The detail

The decline of NAD+ in aging human tissue is a correlation observed in skin samples. It does not establish that raising NAD+ by injection reverses an age-related outcome, and in the precursor trials biochemical target engagement did not reliably translate into improved functional outcomes.

  1. Grant R, et al. A pilot study investigating changes in the human plasma and urine NAD+… Front Aging Neurosci. 2019.
  2. Yu X, et al. Effect of nicotinamide adenine dinucleotide on heart failure caused by… Am J Cardiovasc Drugs. 2026.
  3. Massudi H, et al. Age-associated changes in oxidative stress and NAD+ metabolism in human… PLoS One. 2012.
  4. Martens CR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and… Nat Commun. 2018.
  5. Yoshino M, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in… Science. 2021.
  6. Gallagher C, Emmanuel OO. NAD+ supplementation for anti-aging and wellness: a PRISMA-guided… Ageing Res Rev. 2026.
Important Safety Information

Serious risks

  • Rate appears to be the variable that matters: the one controlled study using a slow six-hour infusion recorded no adverse events, while a clinic series in which patients set their own speed reported moderate to severe symptoms throughout

Commonly reported

  • Nausea
  • Abdominal cramping
  • Chest pressure
  • A faster heart rate
  • These are commonly reported during the infusion and settle once it finishes

Because it is an injection

  • This prescription is subcutaneous rather than intravenous
  • With any injection there can be soreness, redness or swelling where you inject

Most of what is documented comes from intravenous NAD+. Your provider reviews cancer history, kidney and liver function, medications and pregnancy status before prescribing, because a coenzyme sitting inside cellular energy and repair pathways is not neutral in every body. Human safety data for compounded subcutaneous NAD+ is limited, which is the reason this sits with a clinician rather than in a shopping cart.

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