SEXUAL VITALITY
PT-141
Explore a different approach to low sexual desire. Compounded prescription PT-141, with individualized clinician guidance and follow-up included.
From $129/mo
Oral tablet
Sildenafil
Sildenafil contains the same active ingredient as Viagra and is prescribed as the FDA-approved generic after clinician review, then dispensed by a licensed US pharmacy.
Your treatment plan
From $29/month equivalent
- Licensed clinicians
- FDA-approved generic medication
- No clinic visit
- Generic for Viagra
Questions before you start?
Compare this treatmentWhat will I pay?
Standard plan price$29 per month equivalent, billed $87 every 3 months. 3-month commitment.
Billing options and renewal
25 mg monthly plan: $49 billed monthly · 10 tablets total plan quantity. 25 mg quarterly plan: $87 every 3 months · 30 tablets total plan quantity. 50 mg monthly plan: $49 billed monthly · 16 tablets total plan quantity. 50 mg quarterly plan: $87 every 3 months · 48 tablets total plan quantity. Each quarterly option is paid up front for a three-month commitment ($29 per month equivalent). These are recurring prices before any eligible first-order discount. A first-order offer reduces that order only; renewal uses the standard price for the chosen plan. A monthly equivalent is not a monthly charge.
What should I know about this treatment?
Sildenafil contains the same active ingredient as Viagra and is prescribed as the FDA-approved generic after clinician review, then dispensed by a licensed US pharmacy.
Read the evidence and its limitationsWhat should I review before starting?
A licensed clinician reviews your health history and medications and determines whether treatment is appropriate for you.
Read the full Important Safety InformationHow do I request Sildenafil online?
Complete the online assessment with your health history, current medications and treatment goals. A licensed clinician reviews the information and decides whether to prescribe. If prescribed, a licensed pharmacy prepares and ships your medication.
See how care worksWhat It Is
An established option for the moments you choose.
Sildenafil helps you get and maintain an erection with sexual stimulation. Taken before anticipated sex, it offers an as-needed approach to ED treatment without a daily medication routine.6
AnthologyRX offers the FDA-approved generic with the same active ingredient as Viagra. It is usually taken about an hour before sex, following your prescription. A high-fat meal can delay absorption, so timing and meals are useful details to discuss if the response is inconsistent.6
If you want a longer response window or a daily routine, tadalafil offers other schedules to compare. Choosing well means considering what works for your erections and what fits the way you live.
- FDA-approved prescribing information, VIAGRA (sildenafil citrate) tablets, Pfizer Laboratories Div Pfizer Inc, label published February 2026.DailyMed
Who It's For
For men who want the deepest evidence first.
01
The First Prescription
You want to begin with the category’s best-known reference point rather than the newest formulation. Sildenafil gives your clinician decades of clinical experience to work from.
02
The Occasional User
You want treatment when it is relevant, not a medication in your routine every day. Sildenafil is built around an on-demand pattern.
03
The Evidence-First Patient
You care less about novelty than about knowing what a medication does, what it does not do, and where the risks are already well mapped.
Describe your pattern honestly in the assessment. A licensed provider reviews your history and determines the right starting dose, or whether to start at all.
This might not be the right fit if:
- Any use of nitrate medications, including nitroglycerin and isosorbide; combining sildenafil with nitrates can cause a dangerous drop in blood pressure
- Recent heart attack or stroke, or cardiac status your provider considers unstable
- Severe hypotension, or blood pressure that is not adequately controlled
- Alpha-blocker therapy requires provider caution around dosing and timing
- History of non-arteritic anterior ischemic optic neuropathy or certain retinal conditions, at your provider’s discretion
Your intake screens for all contraindications. Every candidate is evaluated by a licensed clinician before any prescription is issued. No prescription is issued without clearance.
Your Plan
Sildenafil, prescribed with care.
FDA-approved generic medication. Prescribed by a licensed provider after clinical review.
- Format
- Oral tablet
- Billed amount
- $87 every 3 months
- Monthly equivalent
- $29 per month
- Commitment
- 3 months
- Monthly option
- $49 billed monthly
- 25 mg monthly plan
- $49 billed monthly · 10 tablets total plan quantity
- 25 mg quarterly plan
- $87 every 3 months · 30 tablets total plan quantity
- 50 mg monthly plan
- $49 billed monthly · 16 tablets total plan quantity
- 50 mg quarterly plan
- $87 every 3 months · 48 tablets total plan quantity
- Fees
- Included in the plan price
Compare billing options and longer-term costs
FDA-approved generic medication
Sildenafil
Oral tablet · 25mg / 50mg
From $29
Monthly equivalent. All fees included.
$87 billed every 3 months. 3-month commitment.
- Licensed clinician review of cardiovascular history and current medications
- Sildenafil prescribed only when the provider determines it is appropriate
- Practical use and interaction guidance supplied as part of the plan
- Ongoing access for response, tolerability, and treatment changes
$29 /mo equivalent · 3-month commitment
$29/mo equivalent, all-in. Consultation is included in the plan price, not added on top. Consultation, cancellation and refund policy.
What happens when I start?
You'll begin an online assessment for Sildenafil.
- Tell your clinician about you. Share your goals, health history and current medications.
- Review your plan. Confirm the treatment option, billing interval and total shown in the assessment.
- Get an individual clinical review. Your clinician decides whether to prescribe. If prescribed, a licensed pharmacy fulfills your prescription.
Starting an assessment doesn't guarantee a prescription. How care works
Prescription issued subject to provider judgment. Results vary. Not a guarantee of outcomes.
*Price reflects a 3-month commitment. See billing details above.
Your subscription renews at your selected billing interval. Cancel through your member dashboard before the next billing date to stop future charges. Cancellation does not refund the current billing period. See cancellation and refund terms.
Have a question about this plan?
Clinical questions
Message your provider about dosing, side effects, your response or changes in your health.
Open patient portalNew to AnthologyRX? Ask our team about getting started.
The people behind your care
Guidance from the first question onward.
Independent clinical care
Licensed clinicians affiliated with Arora Health & Aesthetics, LLC review your health history, medications and goals, then discuss whether Sildenafil or another approach fits your needs.
Medical information on this page reviewed by Dr. Dylan Russell, MD, Chief Health Officer on . Your prescribing clinician provides your individual care.
Verify Dr. Russell's medical licensePrescription pharmacy care
Sildenafil is offered as an FDA-approved generic medication, dispensed by a licensed pharmacy after your clinician issues a prescription.
Your clinician explains the intended use, including whether it falls outside the medication's FDA-approved indications.
Pharmacy & fulfillment
Pharmacies by treatment option
- GoGoMedsFormulation: 25 mg tabletsThis option is not available in South Carolina.Verify: Oklahoma nonresident pharmacy permit 99-8080The current listed 25 mg option is FDA-approved generic sildenafil labeled by Exelan Pharmaceuticals, Inc. Read the product label. Your prescription label identifies the product dispensed.
- HealthWarehouse.comFormulation: 50 mg tabletsVerify: Oklahoma nonresident pharmacy permit 99-7707
Availability depends on your prescription and location. For pharmacy questions, contact our team.
A direct line for follow-up
Message your provider through the patient portal about dosing, side effects, your response or changes in your health. Contact AnthologyRX support for billing, shipment or portal-access help.
The Evidence
What the research shows
69 percent of intercourse attempts succeeded on sildenafil versus 22 percent on placebo.
5.9 vs 1.5
mean successful attempts per month on sildenafil against placebo
The detail
In the two sequential double-blind registration studies, 532 men were randomized to sildenafil 25, 50 or 100 mg or placebo in a 24-week dose-response study, and 329 different men entered a 12-week flexible dose-escalation study. In the last four weeks of the dose-escalation study, 69 percent of all attempts at sexual intercourse were successful on sildenafil compared with 22 percent on placebo, and the mean number of successful attempts per month was 5.9 versus 1.5.1
Across causes of erectile dysfunction, more men reported improved erections than on placebo.
67 to 86% vs 24%
men reporting improved erections across the sildenafil dose groups
The detail
In a 12-week randomized, double-blind, placebo-controlled fixed-dose trial in 514 men whose erectile dysfunction was organic in 32 percent of cases, psychogenic in 25 percent and mixed in 43 percent, sildenafil significantly increased the ability to achieve and maintain erections at all three doses, and 67 to 86 percent of men across the sildenafil groups reported improved erections compared with 24 percent on placebo.2
In men with diabetes, 56 percent reported improved erections versus 10 percent on placebo.
61% vs 22%
men with at least one successful attempt at intercourse
The detail
In a 12-week multicenter randomized, double-blind, placebo-controlled trial in 268 men with diabetes of about 12 years duration and erectile dysfunction of about 5.6 years, 56 percent of men on sildenafil reported improved erections compared with 10 percent on placebo, and 61 percent versus 22 percent had at least one successful attempt at intercourse.3
Pooled across trials, successful intercourse attempts were higher on sildenafil than placebo.
57% vs 21%
successful intercourse attempts pooled from 14 flexible-dose trials
The detail
In a systematic review and meta-analysis of 27 randomized trials covering 6659 men, results pooled from 14 parallel-group flexible-dose trials showed a higher percentage of successful intercourse attempts on sildenafil than on placebo, 57 percent versus 21 percent, weighted mean difference 33.7, 95 percent confidence interval 29.2 to 38.2, and a greater proportion of men with at least one intercourse success during treatment, 83 percent versus 45 percent, relative benefit increase 1.8, 95 percent confidence interval 1.7 to 1.9.4
Sildenafil 50 mg led the starting doses on efficacy and on adverse events alike.
50 mg
starting dose with the greatest efficacy and the highest adverse-event rate
The detail
In a network meta-analysis of 82 randomized trials covering 47,626 patients, sildenafil 50 mg had the greatest efficacy of the starting doses compared, and also the highest overall rate of adverse events; tadalafil 10 mg had intermediate efficacy with the lowest overall adverse-event rate. The comparison is a trade-off between the two, not a ranking on efficacy alone.5
What it does not show
The trials measured intercourse-attempt success, not sexual desire.
The detail
The endpoints are self-reported intercourse-attempt success and questionnaire scores, collected over 12 to 24 weeks in men who had a partner and were attempting intercourse. They establish that erections adequate for intercourse become more frequent. They do not establish an effect on sexual desire, and the FDA-approved labeling states that sildenafil at recommended doses has no effect in the absence of sexual stimulation.146
Placebo did not do nothing: 45 percent of men on placebo recorded at least one success.
45%
men on placebo with at least one intercourse success during treatment
Nothing establishes that sildenafil treats the underlying cause, or that benefit persists after stopping.
more than 3000 men
studied across 21 randomized double-blind placebo-controlled trials
The detail
The FDA-approved labeling describes 21 randomized, double-blind, placebo-controlled trials of up to six months in more than 3000 men aged 19 to 87. That programme establishes an effect while the medication is being taken. It does not establish that sildenafil treats the underlying cause of erectile dysfunction, or that any benefit persists once treatment stops.6
No best drug for an individual, and combinations with other treatments are not recommended.
The detail
The class evidence does not name a best drug for an individual, and it does not extend to stacking. In the network meta-analysis the highest-efficacy starting dose was also the highest-adverse-event starting dose. Separately, the labeling states that the safety and efficacy of combinations of sildenafil with other PDE5 inhibitors or with other treatments for erectile dysfunction have not been studied and that such combinations are not recommended.56
- Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of erectile dysfunction Sildenafil… N Engl J Med. 1998.
- Montorsi F, McDermott TE, Morgan R, Olsson A, Schultz A, Kirkeby HJ, Osterloh IH. Efficacy and safety of fixed-dose oral sildenafil in the treatment of… Urology. 1999.
- Rendell MS, Rajfer J, Wicker PA, Smith MD. Sildenafil for treatment of erectile dysfunction in men with diabetes… JAMA. 1999.
- Fink HA, Mac Donald R, Rutks IR, Nelson DB, Wilt TJ. Sildenafil for male erectile dysfunction: a systematic review and… Arch Intern Med. 2002.
- Chen L, Staubli SE, Schneider MP, Kessels AG, Ivic S, Bachmann LM, Kessler TM. Phosphodiesterase 5 inhibitors for the treatment of erectile… Eur Urol. 2015.
- FDA-approved prescribing information, VIAGRA (sildenafil citrate) tablets, Pfizer Laboratories Div Pfizer Inc, label published February 2026.DailyMed
Important Safety Information
Do not use if you have
- Nitrates in any form or riociguat, because the combination can drop blood pressure dangerously
Serious risks
- An erection lasting longer than four hours needs emergency care, because untreated priapism can cause permanent penile tissue damage
- Sudden loss of vision in one or both eyes, or a sudden decrease or loss of hearing, means stopping the medication and seeking medical attention immediately
Commonly reported
- Headache
- Flushing
- Indigestion
- Nasal congestion
- A temporary change in color vision, usually a blue tinge or trouble telling blue from green
These are the effects reported most often, and they were reported more frequently at higher doses in the trials behind the label. Two less common problems are the reason the labeling is emphatic. Alpha-blockers, other blood-pressure medicines, recent cardiac events and the cardiac demand of sexual activity itself are all part of the review before it is prescribed. Sildenafil is an FDA-approved generic dispensed by a licensed US pharmacy, and whether it is appropriate, and at what dose, is a decision your clinician makes from your full intake.
Questions
Asked and answered.
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