SEXUAL VITALITY
PT-141
Explore a different approach to low sexual desire. Compounded prescription PT-141, with individualized clinician guidance and follow-up included.
From $129/mo
Oral tablet
Tadalafil 5mg Daily
Once-daily tadalafil helps improve erections with sexual stimulation, without timing each dose around sex.
Your treatment plan
From $39/month equivalent
$117 billed every 3 months3-month commitment$59 billed monthly also availableAll fees includedView plan details
- Licensed clinicians
- FDA-approved generic medication
- No clinic visit
- Generic for Cialis (daily)
Questions before you start?
Compare this treatmentWhat will I pay?
Standard plan price$39 per month equivalent, billed $117 every 3 months. 3-month commitment.
Billing options and renewal
The standard Tadalafil 5mg Daily price is $59 billed monthly, or $117 paid up front every three months ($39 per month equivalent; a three-month commitment). These are recurring prices before any eligible first-order discount. A first-order offer reduces that order only; renewal uses the standard price for the chosen plan. A monthly equivalent is not a monthly charge.
What should I know about this treatment?
Once-daily tadalafil helps improve erections with sexual stimulation, without timing each dose around sex.
Read the evidence and its limitationsWhat should I review before starting?
A licensed clinician reviews your health history and medications and determines whether treatment is appropriate for you.
Read the full Important Safety InformationHow do I request Tadalafil 5mg Daily online?
Complete the online assessment with your health history, current medications and treatment goals. A licensed clinician reviews the information and decides whether to prescribe. If prescribed, a licensed pharmacy prepares and ships your medication.
See how care worksWhat It Is
Less planning. More possibility.
Daily tadalafil helps you get and maintain an erection with sexual stimulation, without timing each dose around sex. Taken as prescribed at about the same time each day, it makes treatment part of your routine so intimacy can happen on your terms.3
Tadalafil is the active ingredient in Cialis. AnthologyRX offers the FDA-approved generic, with a 5 mg daily plan. It supports your response to arousal; it does not create a constant erection or increase sexual desire.3
A daily plan can suit regular intimacy or a preference for less advance planning. If you would rather take medication only when needed, on-demand tadalafil or sildenafil offers a different routine. Your health history, other medications, and experience with treatment help determine the fit.
- FDA-approved prescribing information, CIALIS (tadalafil) tablets, Eli Lilly and Company, label published June 2026.DailyMed
Who It's For
A daily routine. Room for spontaneity.
01
Less advance planning
You want to separate taking your medication from deciding when to have sex.
02
Regular intimacy
Sex is a regular part of your life, and you prefer one consistent treatment routine.
03
A different schedule
An on-demand medication helped your erections, but its timing did not fit. A daily option is worth discussing.
Bring your treatment history to the assessment. Frequency, health history and personal preference all factor in, and your provider makes the candidacy call from your full intake rather than from assumptions.
This might not be the right fit if:
- Any use of nitrate medications, including nitroglycerin and isosorbide; combining tadalafil with nitrates can cause a dangerous drop in blood pressure
- Recent heart attack or stroke, or cardiac status your provider considers unstable
- Severe hypotension, or blood pressure that is not adequately controlled
- Alpha-blocker therapy requires provider caution around dosing and timing
- Use of riociguat, or a prior serious reaction to tadalafil
Your intake screens for all contraindications. Every candidate is evaluated by a licensed clinician before any prescription is issued. No prescription is issued without clearance.
Your Plan
Tadalafil 5mg Daily, prescribed with care.
FDA-approved generic medication. Prescribed by a licensed provider after clinical review.
- Format
- Oral tablet
- Strength
- 5 mg
- Total plan quantity
- 90 tablets
- Billed amount
- $117 every 3 months
- Monthly equivalent
- $39 per month
- Commitment
- 3 months
- Monthly option
- $59 billed monthly · 30 tablets total plan quantity
- Fees
- Included in the plan price
Strength describes the preparation. Total plan quantity is the amount included in that plan, not your dose or dosing schedule. Follow the directions on your prescription.
Compare billing options and longer-term costs
FDA-approved generic medication
Tadalafil 5mg Daily
Oral tablet
From $39
Monthly equivalent. All fees included.
$117 billed every 3 months. 3-month commitment.
- Licensed clinician review of cardiovascular history, medications, and treatment goals
- Daily tadalafil prescribed only when the clinician determines the pattern fits
- Nitrates and other important interaction risks screened before prescribing
- Follow-up available for response, tolerability, and switching treatment patterns
$39 /mo equivalent · 3-month commitment
$39/mo equivalent, all-in. Consultation is included in the plan price, not added on top. Consultation, cancellation and refund policy.
What happens when I start?
You'll begin an online assessment for Tadalafil 5mg Daily.
- Tell your clinician about you. Share your goals, health history and current medications.
- Review your plan. Confirm the treatment option, billing interval and total shown in the assessment.
- Get an individual clinical review. Your clinician decides whether to prescribe. If prescribed, a licensed pharmacy fulfills your prescription.
Starting an assessment doesn't guarantee a prescription. How care works
Prescription issued subject to provider judgment. Results vary. Not a guarantee of outcomes.
*Price reflects a 3-month commitment. See billing details above.
Your subscription renews at your selected billing interval. Cancel through your member dashboard before the next billing date to stop future charges. Cancellation does not refund the current billing period. See cancellation and refund terms.
Have a question about this plan?
Clinical questions
Message your provider about dosing, side effects, your response or changes in your health.
Open patient portalNew to AnthologyRX? Ask our team about getting started.
The people behind your care
Guidance from the first question onward.
Independent clinical care
Licensed clinicians affiliated with Arora Health & Aesthetics, LLC review your health history, medications and goals, then discuss whether Tadalafil 5mg Daily or another approach fits your needs.
Medical information on this page reviewed by Dr. Dylan Russell, MD, Chief Health Officer on . Your prescribing clinician provides your individual care.
Verify Dr. Russell's medical licensePrescription pharmacy care
Tadalafil 5mg Daily is offered as an FDA-approved generic medication, dispensed by a licensed pharmacy after your clinician issues a prescription.
Your clinician explains the intended use, including whether it falls outside the medication's FDA-approved indications.
Pharmacy & fulfillment
Listed dispensing pharmacy
- HealthWarehouse.comFormulation: 5 mg tabletsVerify: Oklahoma nonresident pharmacy permit 99-7707
Availability depends on your prescription and location. For pharmacy questions, contact our team.
A direct line for follow-up
Message your provider through the patient portal about dosing, side effects, your response or changes in your health. Contact AnthologyRX support for billing, shipment or portal-access help.
The Evidence
What the research shows
Both once-daily doses beat placebo on erectile function and intercourse success.
9.7 vs 0.9
erectile-function domain change on tadalafil 5 mg against placebo
The detail
In a 12-week multicenter randomized, double-blind, placebo-controlled trial, 268 men were assigned in a 1:2:2 ratio to placebo, tadalafil 5 mg or tadalafil 10 mg taken once daily. Change from baseline in the International Index of Erectile Function erectile-function domain was 0.9, 9.7 and 9.4 respectively; successful penetration on Sexual Encounter Profile question 2 rose 11.2, 36.5 and 39.4 points; successful intercourse on question 3 rose 13.2, 45.5 and 50.1 points. All comparisons against placebo were significant at p less than 0.001.1
84.5 percent on tadalafil reported improved erections against 28.3 percent on placebo.
84.5% vs 28.3%
men reporting improved erections on tadalafil 5 mg against placebo
The detail
In the same trial, 28.3 percent of men on placebo reported improved erections at endpoint compared with 84.5 percent on tadalafil 5 mg and 84.6 percent on 10 mg, and 8.3 percent on placebo scored in the no-erectile-dysfunction range of 26 to 30 on the erectile-function domain compared with 51.5 percent and 50.5 percent on the two once-daily doses.1
Lower once-daily doses also beat placebo on all three co-primary endpoints.
2.5 mg and 5 mg
once-daily doses that separated from placebo over 24 weeks
The detail
In a 24-week randomized, double-blind, placebo-controlled study at 15 United States centers, following a four-week treatment-free run-in, tadalafil 2.5 mg and 5 mg taken once daily significantly improved erectile function against placebo on all three co-primary endpoints: the erectile-function domain and the mean per-patient percentage of yes responses to Sexual Encounter Profile questions 2 and 3.2
Across the labeled programme, the effect did not diminish over six months.
853 patients
total across two 12-week trials and one 24-week trial
The detail
The FDA-approved labeling describes a once-daily programme of two 12-week trials and one 24-week trial involving 853 patients in total, and reports that in the six-month double-blind study the treatment effect did not diminish over time.3
Median time before stopping was longer on daily tadalafil than on-demand sildenafil.
130 vs 67 days
median time to discontinuation, daily tadalafil against on-demand sildenafil
The detail
In an open-label randomized study in 770 men new to PDE5 inhibitors, median time to discontinuation of assigned treatment was 130 days for tadalafil 5 mg once daily and 67 days for sildenafil 50 mg on demand, with Kaplan-Meier discontinuation estimates of 52.2 percent and 66.7 percent respectively.4
What it does not show
Daily dosing has not been shown to work better than on-demand dosing.
p = 0.359
no difference between once-daily and on-demand in the randomized comparison
The detail
Once-daily dosing has not been shown to work better than on-demand dosing. In the randomized comparison above, improvement in the erectile-function domain did not differ between tadalafil once daily, tadalafil on demand and sildenafil on demand, least-squares means 9.4 to 10.0, p equals 0.359. In a pooled comparison of 17 on-demand and 4 once-daily placebo-controlled studies covering 4354 men, the authors concluded that no clinical population appeared to benefit overwhelmingly from one dosing regimen over the other, and that comparison was descriptive rather than a randomized head-to-head. The case for daily dosing is fit and persistence, not superior efficacy.45
More men preferred on-demand dosing, and the scheduled arm was not this dose.
57.8% vs 42.2%
preferred on-demand tadalafil over the scheduled regimen
The detail
Preference is real, and it splits. In an open-label crossover study of 4262 men in 14 European countries, 57.8 percent preferred tadalafil 20 mg on demand and 42.2 percent preferred the scheduled regimen. That scheduled arm was 20 mg three times per week, not the low once-daily dose prescribed here, so it is preference evidence about a related schedule rather than this one.6
Nothing here shows the effect persists after the medication is stopped.
12 to 24 weeks
the length of the once-daily trials behind the label
The detail
The once-daily trials ran 12 to 24 weeks and the labeled programme totals 853 patients. That establishes an effect that held up over six months of continuous dosing. It does not establish that continuous exposure restores erectile function that persists after the medication is stopped, and it does not describe outcomes beyond those durations.123
It does not cure erectile dysfunction, and it does nothing without sexual stimulation.
The detail
A daily schedule does not change what the drug does. The endpoints remain self-reported intercourse success and questionnaire scores. The FDA-approved labeling states that tadalafil has no effect in the absence of sexual stimulation, and the patient labeling states that the medication does not cure erectile dysfunction and does not increase sexual desire.3
- Porst H, Giuliano F, Glina S, Ralph D, Casabe AR, Elion-Mboussa A, Shen W, Whitaker JS. Evaluation of the efficacy and safety of once-a-day dosing of tadalafil… Eur Urol. 2006.
- Rajfer J, Aliotta PJ, Steidle CP, Fitch WP, Zhao Y, Yu A. Tadalafil dosed once a day in men with erectile dysfunction: a… Int J Impot Res. 2007.
- FDA-approved prescribing information, CIALIS (tadalafil) tablets, Eli Lilly and Company, label published June 2026.DailyMed
- Buvat J, Buttner H, Hatzimouratidis K, Vendeira PA, Moncada I, Boehmer M, Henneges C, Boess FG. Adherence to initial PDE-5 inhibitor treatment: randomized open-label… J Sex Med. 2013.
- Brock G, Ni X, Oelke M, Mulhall J, Rosenberg M, Seftel A, D'Souza D, Barry J. Efficacy of continuous dosing of tadalafil once daily vs tadalafil on… J Sex Med. 2016.
- Mirone V, Costa P, Damber JE, Holmes S, Moncada I, Van Ahlen H, Wespes E, Cordell WH, Chan M, Lembo D, Varanese L. An evaluation of an alternative dosing regimen with tadalafil, 3… Eur Urol. 2005.
Important Safety Information
Do not use if you have
- Nitrates in any form are an exclusion
- Riociguat, a guanylate cyclase stimulator — a labeled contraindication for the same reason, and an exclusion as well
Serious risks
- An erection lasting longer than four hours needs emergency care
- Sudden loss of vision in one or both eyes, or a sudden decrease or loss of hearing, means stopping the medication and seeking medical attention right away
Commonly reported
- Headache
- Indigestion
- Nasal and upper-airway symptoms
- Back pain
- Muscle aches
- Flushing
- Back pain and muscle aches generally began 12 to 24 hours after a dose and typically settled within 48 hours
Because it is taken daily
- A daily dose keeps tadalafil in your system continuously, so anything that interacts with it can interact at any time
- That is why nitrates in any form are an exclusion, and why alpha-blockers and other blood-pressure medicines are reviewed carefully
These are the effects reported most often in the once-daily trials behind the label. Recent cardiac events and the cardiac demand of sexual activity itself are the real subject of the cardiovascular questions in your intake. Tadalafil is an FDA-approved generic dispensed by a licensed US pharmacy, and whether the daily pattern fits your health profile, and not only your preference, is your clinician's decision.
Questions
Asked and answered.
Explore
More in Sexual Vitality.
SEXUAL VITALITY
Oxytocin
A clinician-guided compounded oxytocin nasal spray for people exploring the social and emotional layer of intimacy.
From $99/mo
COMBINATION THERAPY
Tadalafil + Sildenafil RDT
A clinician-selected compounded rapid-dissolve tablet that brings two familiar timing profiles into one individualized prescription.
From $49/mo
